Molecular detection of M. tuberculosis complex with first-line (isoniazid, rifampicin) and second-line drug-resistance mutations by reverse hybridisation.
MDR-TB requires rapid recognition. LPA extends molecular resistance testing beyond rifampicin to isoniazid (katG, inhA) and — with second-line LPA — fluoroquinolones and injectables, within days rather than weeks.
Isoniazid and rifampicin are the backbone of first-line TB therapy; resistance to both defines MDR-TB. Rapid genotypic profiling shortens the time to an appropriate regimen.
LPA identifies MTB complex and the commonest resistance-conferring mutations directly from smear-positive specimens or cultured isolates, enabling earlier regimen adjustment.
Sterile container · Cap: White
Additive: None
Volume: 3–5 mL
Collect early-morning deep-cough sample for mycobacterial testing.
Validated target list: data to be updated. Please contact ID Labs for the current configuration.
| Characteristic | Value | Source |
|---|---|---|
| Analytical / clinical performance | Performance characteristics: please contact ID Labs — data to be updated. | ID Labs Validated Performance |
World Health Organization
WHO Guidelines · 2021 (updated)
WHO recommendations on rapid molecular diagnostics for TB, including Xpert MTB/RIF and line probe assays, and their place within diagnostic algorithms. These are international guidelines; they do not constitute ID Labs validated performance data.
Scientific Reports (Nature) · 2015
Curated peer-reviewed / authoritative reference. Open the source link for the full text.
Frontiers in Microbiology · 2018
Curated peer-reviewed / authoritative reference. Open the source link for the full text.
Rapid automated molecular detection of M. tuberculosis complex and rifampicin resistance directly from sputum and other specimens.
Automated liquid culture of mycobacteria with phenotypic drug susceptibility testing — the reference pathway for confirming viable TB and defining resistance.
Panel configuration, specimen logistics and turnaround details on request.
Information on this page is educational and does not replace professional clinical judgment. Performance values are labelled by source (ID Labs Specification / ID Labs Validated Performance / Manufacturer Specification / Published Scientific Evidence). Molecular results must be correlated clinically and, where appropriate, confirmed by culture and phenotypic susceptibility testing.
